Jianxi Xiao

Ph.D., Professor


Jianxi Xiao obtained his B.S. degree at Wuhan University in 2004, and Ph.D. degree at Rutgers University-New Brunswick, New Jersey, USA in 2009. He continued his postdoc studies at Rutgers University from 2009 to 2011. His research focused on the biophysical characterization of collagen mimetic peptides in order to elucidate the underlying mechanism of Osteogenesis Imperfecta. Dr. Xiao joined Department of Chemistry at Lanzhou University as Professor in 2012. His current research interest includes: Biophysical characterization of proteins and peptides, Protein-templated biomineralization, Protein and peptide-based materials for tissue regeneration, and Novel assays for the detection of protein biomarkers.


Representative Publications

1. X. Cai, Z. Liu, S. Zhao, C. Song, S. Dong and J. Xiao. A single stranded fluorescent peptide probe for targeting collagen in connective tissues. Chemical Communications, 2017, 53, 11905-11908.

2.  M. He, Y. Zhang, J. Munyemana, T. Wu, Z. YangH. Chen, W. Qu, and J. Xiao. Tuning the hierarrchical nanostructure of hematite mesocrystals by collagen-templated biomineralization. Journal of Materials Chemistry B, 2017, 5, 1423-1429.

3. X. Cai, Q. Yang, J. Ding, W. Ye, X. Li, and J. Xiao. Paper-based FRET for direct detection of collagen triple helix. Journal of Materials Chemistry B, 2016, 4, 7009-7013.

4. M. He, L. Wang, J. Wu and J. Xiao. Ln3+-Mediated Self-Assembly of a Collagen Peptide into Luminescent Banded Helical Nanoropes. Chemistry - A European Journal, 2016, 22, 1914-1917.

5. X. Sun, J. Fan, W. Ye, H. Zhang, Y. Cong and J. Xiao. A Highly Specific Graphene Platform for Sensing Collagen Triple Helix. Journal of Materials Chemistry B, 2016, 4, 1064-1069.

6. X. Sun, J. Fan, X. Li, S. Zhang, X. Liu and J. Xiao. Colorimetric and Fluorometric Monitoring of the Helix Composition of Collagen Peptides at nM level. Chemical Communications, 2016, 52, 3107-3110.

7. X. Sun, J. Fan, Y. Zhang, H. Chen, Y. Zhao and J. Xiao. A graphene oxide-based FRET sensor for rapid and specific detection of unfolded collagen fragments. Biosensors and Bioelectronics, 2016, 79, 15-21.

8. J. Xiao, X. Sun, M. Balaram, B. Brodsky and J. Baum. NMR Studies Demonstrate a Unique AAB Composition and Chain Register for a Heterotrimeric Type IV Collagen Model Peptide Containing a Natural Interruption Site. Journal of Biological Chemistry, 2015, 90, 24201-24209.

9. J. Xiao, R.M. Addabbo, J.L. Lauer, G.B. Fields, and J. Baum. Local conformation and dynamics of isoleucine in the collagenase cleavage site provides recognition signal for matrix metalloproteinases. Journal of Biological Chemistry, 2010, 285, 34181.

10. J. Xiao and J. Baum. Structural insights from 15N relaxation data for an anisotropic collagen peptide. Journal of the American Chemical Society, 2009, 131, 18194.



Room 311, the Second Chemistry Building





1999-2003, Wuhan University, B.S.

2004-2009, Department of Chemistry and Chemical Biology, Rutgers University-New Brunswick, Ph.D.

2009-2011, Department of Chemistry and Chemical Biology, Rutgers University-New Brunswick, Postdoc Associate