Yanlong Yang

Ph.D., Associate Professor

Introduction

Yan-Long Yang received a B.S. degree from Sichuan University in 2010. He then obtained his Ph.D from the Kunming Instituete of Botany, Chinese Academy of Science, under the guidance of Professor Ying Zeng in 2016. After that, he went to Institute of Microbiology, Chinese Academy of Science as an assistant professor in professor Hongwei Liu's group (2016-2017). In 2017, he became an associate professor at College of Chemistry and Chemical Engineering, Lanzhou University. Since his Ph.D project, he has been working on the biosynthesis of natural products from high fungi. The main research interests in his group are discovery and biosynthesis of bioactive natural products from higher fungi.


Representative Publications

1. Yang, Y-L., Zhang, Y., Zhang, S., Chen, Q., Ma, K., Bao, L., Tao, Y., Yin, W-B., Wang, G., Liu, H-W. Identification and Characterization of a Membrane-Bound Sesterterpene Cyclase from Streptomyces somaliensis. J. Nat. Prod. 2018, 81, 1089-1092.

2. Yang, Y-L., Zhang, S-S., Ma, K., Xu, Y-X., Tao, Q-Q., Chen, Y-H., Chen, Juan., Guo, S-X., Ren, J-W., Wang, W-Z., Tao, Y., Yin, W-B., Liu, H-W. Discovery and Characterization of a New Family of Diterpene Cyclases in Bacteria and Fungi. Angew. Chem. Int. Ed. Engl. 2017, 56, 4749-4752.

3. Yang, Y-L., Tao, Q-Q., Han, J-J., Bao, L., Liu, H-W. Recent Advance on Bioactive Compounds from the Edible and Medicinal Fungi in China. Medicinal Plants and Fungi: Recent Advances in Research and Development. 2017, pp 253-312.

4. Yang, Y-L., Zhou, H., Du, G., Feng K-N., Feng, T., Fu, X-L., Liu, J-K., Zeng, Y.  A monooxygenase from Boreostereum vibrans catalyzes oxidative decarboxylation in a divergent vibralactone biosynthesis pathway. Angew. Chem. Int. Ed. Engl. 2016, 55, 5463-5466.

5. Tao, Q-Q. #, Ma, K. #, Yang, Y-L. #, Wang, K., Chen, B-S., Huang, Y., Han, J-J., Bao, Li., Liu, X-B., Yang, Z-L., Yin, W-B., Liu, H-W. Bioactive Sesquiterpenes from the Edible Mushroom Flammulina velutipes and Their Biosynthetic Pathway Confirmed by Genome Analysis and Chemical Evidence. J. Org. Chem. 2016, 81, 9867-9877. (#co-first author)

6. Zhao, P-J.*, Yang, Y-L., Du, L-C., Liu, J-K., Zeng, Y*. Elucidating the biosynthetic pathway for vibralactone, a novel pancreatic lipase inhibitor with a fused bicyclic β-lactone. Angew. Chem. Int. Ed. Engl. 2013, 52, 2298-2302.


Office:

Room 3034, the first Chemistry Building

TEL:

E-mail:

ylyang@lzu.edu.cn

Education: