Introduction

Shang-Dong Yang received his B. Sc. (1997) and Ph. D. (2006) in organic chemistry at Lanzhou  University (P. R. China). He worked as a postdoctoral fellow (2006-2007) at Peking  University (P. R. China), working with Prof. Zhang-Jie Shi. Then he moved to The University of Chicago (USA), doing his postdoctoral work (2007-2009) with Prof. Chuan He. He obtained a professor position at Lanzhou University in 2009, and worked at the State Key Laboratory of Applied Organic Chemistry. He was the recipient of the “Program for New Century Excellent Talents in University” in 2011; He also received 2013 the Most Cited of Hundred Papers Award in China, 2015 Thieme Chemistry Journal Award and 2015 Membership Award of the American Chemical Society.

Research Interests:

1.       Transition-metal catalyzed C-P bond formation

2.       Transition-metal catalyzed C-C and C-H bond activation.

Representative Publications

1.“New Approaches for Biaryl-Based Phosphine Ligand Synthesis via P=O Directed C−H Functionalizations”. Ma, Y.-N.; Li, S.-X. and Yang, S.-D.* Acc. Chem. Res. 2017, 50, 1480−1492.

2.“Highly Efficient and Divergent Construction of Chiral γ‑Phosphono-α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated C(sp³)−H Bonds”. Yang, Q.; Yang, S.-D.* ACS Catal. 2017, 7, 5220−5224.

3. “Direct Allylic C−H Bond Activation To Synthesize [Pd(η3‑cin)(IPr)Cl] Complex: Application in the Allylation of Oxindoles”. Hu, R.-B.; Wang, C.-H.; Ren, W.; Liu, Z.; Yang, S.-D.* ACS Catal. 2017, 7, 7400−7404.

4. “Diastereoselective Radical Oxidative C−H Aminations toward Chiral Atropoisomeric (P, N) Ligand Precursors,” Ma, Y.-N.; Cheng, M.-X.; Yang, S.-D.* Org. Lett. 2017, 19, 600−603.

5.“Palladium-Catalyzed Migratory Insertion of Isocyanides for Synthesis of C‑Phosphonoketenimines”. Yang, Q.; Li, C.; Cheng, M.-X.; Yang, S.-D.* ACS Catal. 2016, 6, 4715−4719.

6. “Asymmetric Synthesis of Chiral Atropisomeric Bis-Aryl Organophosphorus from Menthyl H-Phosphinate,” Ma, Y.-N.; Yang, S.-D.*, Chem. Rec. 2016, 16, 977−986.

7.“Enantioselective synthesis of arylglycine derivatives by direct C–H oxidative cross-coupling”, Wei, X.-H.; Wang, G.-W.; Yang, S.-D.* Chem. Commun., 2015, 51, 832–835.

8.“A unique Copper-catalyzed Cross-coupling Reaction by Hydrogen (H₂) Removal for the Stereoselective Synthesis of 3-phosphoindoles”, Zhou, A.-X.; Mao, L.-L.; Wang, G.-W.; Yang, S.-D.* Chemm. Commun. 2014, 50, 8529–8532.

9.“Regio- and Stereoselective Allylic C−H Arylation with Electron-Deficient Arenes by 1,1′-Bi-2-naphthol−Palladium Cooperation”, Wang, G.-W.; Zhou, A.-X.; Li, S.-X.; Yang, S.-D.* Org. Lett. 2014, 16, 3118–3121.

10.“Direct Annulations toward Phosphorylated Oxindoles by Silver-Catalyzed Carbon-phosphorus Functionalization of Alkenes”, Li, Y.-M.; Sun, M.; Wang, H.-L.; Tian, Q.-P.; Yang, S.-D.* Angew. Chem. Int. Ed., 2013, 52, 3972–3976.

Representative Publications