Yueting Wu

Ph.D., Associate Professor

Introduction

Cancer immunotherapy and cancer immunology, cell-to-cell communication between cancer and immune cells. Nanosized biological particles (exosomes) isolated from cancer cells and/or immune cells. A variety of anti-cancer immunoregulating targets and their therapeutic effects, e.g. CTLA-4, PD1/PD-L1, LAG3.


Representative Publications

1. Melanoma exosomes deliver a complex biological payload that upregulates PTPN11 to suppress T lymphocyte function. Pigment Cell Melanoma Res.2017 Mar 7; 30(2):203-218. Yueting Wu, Wentao Deng, Emily Chambers McGinley and David J. Klinke II.

2. Exosomes: improved methods to characterize their morphology, RNA content, and surface protein biomarkers. Analyst. 2015 Sep 14;140(19):6631-42. Yueting Wu, Wentao Deng, and David J. Klinke II.

3. Interlocked positive and negative feedback network motifs regulate beta-catenin activity in the adherens junction pathway. Mol Biol Cell. 2015 Jul 29. pii: mbc.E15-02-0083. David J. Klinke II, Nicolas Horvath, Venessa Cuppett, Yueting Wu, Rania Kanj.

4. Inferring alterations in cell-to-cell communication in HER2+ breast cancer using secretome profiling of three cell models. Biotechnol Bioeng. 2014 Sep;111(9):1853-63. David J. Klinke II, Yogesh M. Kulkarni, Yueting Wu, Christina Byrne-Hoffman.

5. Selective filling of nanowells in nanowell arrays fabricated using polystyrene nanosphere lithography with cytochrome P450 enzymes. Nanotechnology. 2012 Sep; 23 (38): 385101.Lance A. Wollenberg, John E. Jett, Yueting Wu, Darcy R. Flora, Nianqiang Wu, Timothy S. Tracy and Peter M. Gannett.

6. Azathioprine hepatotoxicity and the protective effect of liquorice and glycyrrhizic acid. Phytother Res. 2006 Aug; 20 (8): 640-5.  Wu Yue-ting, Shen Chong, Yin Jian, Yu Jinpeng, Meng Qin.

7. Biodegradation of crude oil by Pseudomonas aeruginosa in the presence of rhamnolipids. J Zhejiang Univ Sci B. 2005 Aug; 6 (8): 725-30. (Indexed by EI, 2005). Zhang Guoliang, Wu Yue-ting, Qian Xinping, Meng Qin. 


Office:

222 South Tianshui Road, Lanzhou, Gansu, 730000, P. R. China

TEL:

E-mail:

wuyt@lzu.edu.cn

Education:

2015-2016 Center For Immunotherapy (CFI), Roswell Park Cancer Institute (RPCI), Buffalo, NY, USA, postdoctoral researcher. 

2009-2015   West Virginia University, Morgantown, WV, USA, Ph.D.

2000-2006 Zhejiang University, B.S. and M.S